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Dextran 40

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Dextran_40
Names
Trade namesLMD, Rheomacrodex, others
Other namesLow viscosity dextran[1]
Clinical data
Drug classColloid[1]
Main usesExpand blood volume[2]
Side effectsVolume overload, kidney problems, acidosis, allergic reactionss, poor blood clotting[2]
Pregnancy
category
External links
AHFS/Drugs.comMonograph
Legal
Legal status
Chemical and physical data
Molar mass70,000 Da

Dextran 40, nke a na-ere n'okpuru akara aha LMD n'etiti ndị ọzọ, bụ ụdị mmiri a na-enye site na ịgbanye n'ime akwara iji gbasaa ogo ọbara.[2] A na-eji ya eme ihe maka ihe mgbu dịka nke ọbara ma ọ bụ ọkụ na-ere mgbe Mgbịnye ọbara anaghị adị ngwa ngwa.[2] Otú ọ dị, ọ naghị ebu oxygen.[3]

Mmetụta nwere ike ịgụnye oke ibu, nsogbu akụrụ, acidosis, mmeghachi ahụ nfụkasị ahụ, na ọbara na-adịghị mma.[2] A naghị atụ aro ya na Ọrịa akụrụ siri ike, ọrịa obi, ma ọ bụ ọrịa mkpụkọ.[2] Ojiji nwere ike igbochi ụfọdụnyocha ọbara.[2]

Dextran 40 malitere iji ya eme ihe n'ụzọ ọgwụ na 1961.[4] Ọ bụ polymer glucose nke nwere ịdị arọ nke 40 kDa.[1][4] Ọ na-arụ ọrụ site na ịdọrọ mmiri site na oghere extravascular n'ime Akwara ọbara.[2] Ọ bụ ihe ngwọta colloid na-abụghị protein. [2][1]

Ntụaka

[dezie | dezie ebe o si]
  1. 1.0 1.1 1.2 1.3 DailyMed - LMD IN DEXTROSE- dextran 40 injection, solution LMD IN SODIUM CHLORIDE- dextran 40 injection, solution. dailymed.nlm.nih.gov. Archived from the original on 14 April 2021. Retrieved on 23 December 2021.
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 Dextran 40 Monograph for Professionals (en). Drugs.com. Archived from the original on 3 January 2017. Retrieved on 22 July 2021.
  3. Howe (10 December 2019). Pharmacology for the Surgical Technologist - E-Book (in en). Elsevier Health Sciences. ISBN 978-0-323-66122-5. Retrieved on 23 December 2021. 
  4. 4.0 4.1 Alexander (10 February 2000). Encyclopedia of Microbiology, Four-Volume Set (in en). Academic Press. ISBN 978-0-08-054848-7. Retrieved on 23 December 2021.