Usòrò:PegUricase.png

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English: A comparison of uricase (pdb:1uox) and PEG-uricase (model). PEG-uricase includes 40 polymers of 10kDa PEG. PEGylation improves its solubility at physiological pH, increases serum half-life and reduces immunogenicity without compromising activity. Upper images show the whole tetramer, lower images show an example of one of the lysines that is PEGylated. (PEG-uricase model from reference[1], only 36 PEG polymers included)
Ǹgụ́ụ̀bọ̀chị̀
Mkpọlọ́gwụ̀ Orü ọnwé
Odé ákwụ́kwọ́ Evolution and evolvability

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I, the copyright holder of this work, hereby publish it under the following license:
w:en:Creative Commons
í-kpó-áhà
This file is licensed under the Creative Commons Attribution 4.0 International license.
I wepulara nóru:
  • i nye – ikọpị,ikekasi na izịpụ ọru a
  • i dowaria – igbanwee ọrụ a
Ọ ga bụ na ọnọdụ ndi a:
  • í-kpó-áhà – Ị ga-enyerịrị ugo kwesịrị ekwesị, nye njikọ na ikikere ahụ, ma gosikwa ma emere mgbanwe. Ị nwere ike ime ya n'ụzọ ezi uche ọ bụla, mana ọ bụghị n'ụzọ ọ bụla na-egosi na onye nyere ikikere kwadoro gị maọbụ ojiji gị.
  1. (3 January 2008). "PEG-uricase in the management of treatment-resistant gout and hyperuricemia.". Advanced drug delivery reviews 60 (1): 59-68. PMID 17826865.

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depicts Bekee

PEGylation Bekee

uricase Bekee

22 Febụwarị 2015

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dị ùgbu â23:50, 21 Febụwarị 2015NvóÁká màkà otù ȯ dị nà 23:50, 21 Febụwarị 20152,192 × 2,136 (1.65 MB)Evolution and evolvabilityUser created page with UploadWizard

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