Ọrịa na-egbochi ọbara ogbugba
Ihe na-egbochi ọbara ọgbụgba (antihæmorrhagic) bụ ihe na-akwalite ọbara ọgbụrụgba (ịkwụsị ọbara ọgburu). A pụkwara ịmara ya dị ka ihe na-ahụ maka hemostatic (nke a na-akpokwa ihe nlereanya ọbara).
Ihe ndị na-egbochi ọbara ọgbụgba a na-eji eme ọgwụ nwere usoro dị iche iche nke esi eziputa ha :
- Ọgwụ sistemụ na-arụ ọrụ site na igbochi fibrinolysis maobu ikwalite Mgbako
- Ndị na-eme ka ọbara na-arụ ọrụ n'ógbè na-arụpụta site na ịkpata vasoconstriction maọbu ịkwalite mkpokọta platelet.
Ụzọ esi emezi ihe ọgwụ[dezie | dezie ebe o si]
A na-eji ihe ndị na-eme ka ọbara ghara ịba n'ahụ n'oge usoro ịwa ahụ iji nweta hemostasis ma kewaa ha dị ka hemostats, sealants na adhesives. Ha dịgasị iche dabere na usoro ha na-arụ ọrụ, ihe mejupụtara, ịdị mfe itinye n'ọrụ, ịrapara na anụ ahụ, immunogenicity na ọnụahịa. Ndị ọrụ ana-enye ohere ngwa ngwa hemostasis, ọhụụ ka mma nke ebe ịwa ahụ, oge ịwa ahụ dị mkpirikpi, belata ihe achọrọ maka mmịnye ọbara, belata oge ọgwụgwọ ọnyá na imeziwanye oge mgbake nke onye ọrịa.[1]
Ụdị[dezie | dezie ebe o si]
Usoro[dezie | dezie ebe o si]
E nwere ọtụtụ ụdị ọgwụ mgbochi ọbara ọgbụgba eji eme ihe na ọgwụ. Ndị a gụnyere ọgwụ fibroid , ihe ndị na-eme ka ọbara kpụkọọ, na vitamin K.[2]
Obodo[dezie | dezie ebe o si]
Ndị na-ahụ maka ọbara na-agbapụta n'oge na-adịghị anya na-enweta ewu ewu maka iji ya na nchịkwa ọbara ọgbụgba mberede, ọkachasị na ọgwụ ndị agha. Ha dị n'ụdị atọ - dị ka ntụ ntụ a wụsara n'ọnyá, dịka mkpisi odee nke ana akpọ statisticsinye ya na uwe.[3][4]
Ihe eji emepụta ihe[dezie | dezie ebe o si]
Ihe nchekwa ọbara[dezie | dezie ebe o si]
Ihe nchekwa ọbara ana akpọ (MCH) bụ ihe na-ahụ maka ihe na-eme n'oge a nke nwere ihe njikọ ọbara. Ọ na-adọta platelets ma na-enye ohere maka mmepụta nke ọbara mgbe ọ na-emetụta ọbara. N'adịghị ka clamp hemostatic, ọ dịghị ihe ọ bụla na-arụ. Dọkịta na-awa ahụ na-agbanye MCH na ebe ọbara na-agba, collagen na-adọta ma na-enyere aka na usoro ọbara iji kwụsị ọbara.[5]
Mmetụta bara uru maka MCH dị iche na nke hemostatic clamp.
Ihe ndị dị elu[dezie | dezie ebe o si]
bụ ihe ndị dị n'elu nke nwere chitosan na nnu ya. Chitosan na ọbara ndị kpokotara ọnụ na mkpụrụ ndụ ọbara uhie na-ejikọta iji mepụta gel-dị ka akpụ nke na-emechi arịa na-agba ọbara. N'adịghị ka teknụzụ hemostat ndị ọzọ, ọrụ ya anaghị achọ ụzọ hemostatic dị mma, ya mere ọ na-aga n'ihu na-arụ ọrụ ọbụna mgbe anticoagulants dị ka heparin dị.[6]
A na-eji Chitosan eme ihe na ụfọdụ hemostats mberede nke e mere iji kwụsị ọbara ọgbụgba na-eyi ndụ egwu. Ojiji ha guzosiri ike n'ọtụtụ ndị agha na ndị na-ahụ maka mmerụ ahụ.[7]
Ihe na-adịghị ndụ[dezie | dezie ebe o si]
Ịkpali kọntaktị[dezie | dezie ebe o si]
Kaolin (na zeolite dị na ya) na-eme ka cascade coagulation rụọ ọrụ, a na-ejikwa ya dị ka akụkụ na-arụ ọrụ nke hemostatic dressings (dịka ọmụmaatụ, na QuikClot).[8]
Ndị na-eme ihe nkiri[dezie | dezie ebe o si]
Ihe mgbochi ọbara (nke a na-akpọkwa stiptic) bụ ụdị ihe na-egbochi ọbara ọgbụgba nke na-arụ ọrụ site na ịbịakọta anụ ahụ iji mechie akwara ọbara merụrụ ahụ. pensụl Styptic nwere ihe na-eme ka ihe dị mma.
Usoro nnyefe a na-ahụkarị maka nke a bụ pensụl styptic ma ọ bụ hemostatic (ekwesịghị ịgbagwoju anya na pensụl caustic). Nke a bụ obere ọgwụ. Anhydrous aluminium sulfate bụ isi ihe na-eme ka oghara ịdị na ya ma na-arụ ọrụ dika ogan na ahụ maka ọbara iji gbochie ọbara na-aga. A na-etinye osisi ahụ kpọmkwem n'ebe ọbara na-agba. Ike ion dị elu na-akwalite flocculation nke ọbara, na kemịkal astringent na-akpata vasoconstriction mpaghara. Tupu e mepụta agụba nchekwa, pensụl styptic bụ akụkụ dị mma nke ihe ịkpụ afụ ọnụ ma jiri ya mee ihe iji mechie ịkpụ afọ.[9] Ụfọdụ ndị mmadụ na-aga n'ihu na-eji pensụl styptic maka obere mmerụ ahụ akpụkpọ ahụ site na nchekwa ma ọ bụ agụba eletrik.[9]
A na-eji ntụ ntụ eme ihe na azụmaahịa anụmanụ iji kwụsị ọbara ọgbụgba site na mbọ ndị a na-egbu egbu. A na-ejikarị ntụ a eme ihe na anụmanụ, dịka nwamba, nkịta na ihe mmụta nke a na-ahụ akwara ya n'etiti mbọ.[10]
Lekwaa[dezie | dezie ebe o si]
- Koodu ATC B02 - Antihemorrhagics
- Mgbochi ọbara
- Mgbasa ọbara TC-325
Edensibia[dezie | dezie ebe o si]
- ↑ Vyas (22 October 2013). "Comparison of hemostatic agents used in vascular surgery". Expert Opinion on Biological Therapy 13 (12): 1663–1672. DOI:10.1517/14712598.2013.848193. PMID 24144261.
- ↑ Pharmacology ReCap 2.0 for Bachelor of Dentistry Students (in en). Quick Review of Pharmacology.
- ↑ Styptic Pencil (definition)
- ↑ When to use hemostatic agents in EMS. EMS1. Archived from the original on 2016-03-15. Retrieved on 2016-03-14.
- ↑ Sundaram (2010-01-01). "Evolution of hemostatic agents in surgical practice". Indian Journal of Urology 26 (3): 374–378. DOI:10.4103/0970-1591.70574. ISSN 0970-1591. PMID 21116358.
- ↑ Millner (2010-10-01). "Chitosan arrests bleeding in major hepatic injuries with clotting dysfunction: an in vivo experimental study in a model of hepatic injury in the presence of moderate systemic heparinisation". Annals of the Royal College of Surgeons of England 92 (7): 559–561. DOI:10.1308/003588410X12699663903593. ISSN 0035-8843. PMID 20522310.
- ↑ Military Experts Say Newer Hemostatic Dressings Beat Gauze // ACEP. www.acep.org. Archived from the original on 2016-03-15. Retrieved on 2016-03-14.
- ↑ HOW QUIKCLOT BRAND PRODUCTS WORK TO STOP BLEEDING. Z-Medica Corporation. Archived from the original on 23 September 2014.
- ↑ 9.0 9.1 Styptic Pencil what is it, how to use at Executive Shaving. Executive-shaving.co.uk (2015-08-21). Archived from the original on 2013-09-01. Retrieved on 2015-10-20.
- ↑ Pet first-aid kit contents. www.vet.cornell.edu. Archived from the original on 2009-07-29. Retrieved on 2016-03-14.