Bentazepam
| Obere ụdị nke | chemical compound  |
|---|---|
| Usoro kemịkalụ | C₁₇H₁₆N₂OS |
| SILES nke canonical | C1=CC=C(C=C1)C2=NCC(=O)NC3=C2C4=C(S3)CCCC4 |
| Subject has role | hypnotics and sedatives |
Me mmadụ
Ọ nwere ihe na-eme ka nchegbu kwụsị, ihe na-egbochi nkụchi, ihe na'ime ka ọ dị jụụ na ekpere chi oboro ndị na eme ka ndị mmadụ ihe na-ehi ụra. A na-enweta ọnụ ọgụgụ kachasị elu nke plasma n'ihe dị ka awa 2.5 mgbe a nwesịrị ọgwụgwọ ọnụ.[1] Ọkara ndụ mwepụ ahụ dị n'etiti ihe dịka awa 2-4.[2][3] Bentazepam dị irè dị ka ihe na-egbochi nchegbu.
Nnukwu benzodiazepine na bentazepam nwere ike ịkpata coma na nsogbu iku ume.[4] Mmetụta ọjọọ gụnyere ọnụ kpọrọ nkụ, ụra, asthenia, dyspepsia, afọ mgbu, agbọ onunu[5] na ọgwụ na-akpata lymphocytic colitis ejikọtara ya na bentazepam.[6][7] A na-ejikọkwa mmerụ ahụ imeju siri ike na ịba ọcha n'anya na bentazepam.[8][9][10] Ọ bụ ezie na a na-ewere ọdịda imeju site na bentazepam dị ka ihe a na-adịghị ahụkebe, a tụwo aro nlekota ọrụ imeju maka ndị ọrịa niile na-aṅụ bentazepam.[11]
Hụkwa
[dezie | dezie ebe o si]- Ndepụta nke benzodiazepines
Ntụaka
[dezie | dezie ebe o si]- ↑ "Parametrization by non-linear regression and bayesian estimation of bentazepam in a multiple dosage regimen in humans". International Journal of Clinical Pharmacology, Therapy, and Toxicology. 25 (11): 627–32. November 1987. PMID 3429066.
- ↑ "Pharmacokinetics of tiadipone: a new anxiolytic". International Journal of Clinical Pharmacology, Therapy, and Toxicology. 24 (9): 482–4. September 1986. PMID 2877954.
- ↑ "Open-loop feedback control of serum bentazepam concentrations and Bayesian estimation in multiple dosage regimens in patients". International Journal of Clinical Pharmacology, Therapy, and Toxicology. 29 (11): 457–62. November 1991. PMID 1800395.
- ↑ "[Mixed benzodiazepine poisoning and reversal with flumazenil (Ro 15-1788)]". Revista Espanola de Anestesiologia y Reanimacion. 36 (1): 48–50. 1989. PMID 2565591.
- ↑ "[A pharmacovigilance study with bentazepam in a sample of 1046 psychiatric outpatients]". Revista de Medicina de la Universidad de Navarra. 34 (2): 80–8. 1990. PMID 1983365.
- ↑ "Collagenous and lymphocytic colitis. evaluation of clinical and histological features, response to treatment, and long-term follow-up". The American Journal of Gastroenterology. 98 (2): 340–7. February 2003. doi:10.1111/j.1572-0241.2003.07225.x. PMID 12591052.
- ↑ "Bentazepam-induced hepatic bridging necrosis". Journal of Clinical Gastroenterology. 25 (4): 710–1. December 1997. doi:10.1097/00004836-199712000-00042. PMID 9451703.
- ↑ "Outcome of acute idiosyncratic drug-induced liver injury: Long-term follow-up in a hepatotoxicity registry". Hepatology. 44 (6): 1581–8. December 2006. doi:10.1002/hep.21424. PMID 17133470.
- ↑ Tuca, Albert (2003). "Utilidad clinica del acetato de megestrol para la ganancia de peso en los enfermos con neoplasia y caquexia". Medicina Clinica (in Spanish). 120 (17): 678. doi:10.1157/13047309.
- ↑ "Bentazepam-associated chronic liver disease". Lancet. 343 (8901): 860. April 1994. doi:10.1016/S0140-6736(94)92065-6. PMID 7908109.
- ↑ "Chronic liver injury related to use of bentazepam: an unusual instance of benzodiazepine hepatotoxicity". Digestive Diseases and Sciences. 45 (7): 1400–4. July 2000. doi:10.1023/A:1005520523502. PMID 10961721.