Fludiazepam
Fludiazepam, nke a na-ere n'okpuru aha Erispan (エリスパン) bụ benzodiazepine dị ike na 2ʹfluoro sitere na diazepam, bụ nke Hoffman-La Roche mepụtara na 1960s.[1][2][3][4][5] A na-ere ya na Japan na Taiwan. [mkpa nhota] Ọ na-arụ ọrụ ọgwụ ya site na ịkwalite mgbochi GABAergic.[6] Fludiazepam nwere okpukpu anọ karịa njikọ maka ndị na-anabata benzodiazepine karịa diazepam.[7] Ọ nwere ihe na-eme ndị mmadụ n'ihe ndị na em ka nchegbu kwụsị, ihe na-egbochi nkụchi, ihe na'ime ka ahụ dị jụụ, ihe na na-emebi ihe na-emetụta ahụike.[8][9][10][11] A na-eji Fludiazepam eme ihe ntụrụndụ.[12]
Hụkwa[dezie | dezie ebe o si]
- Diazepam
- Diclazepam (nke yiri 2ʹ-chloro)
- Difludiazepam (nke sitere na 2',6'-difluoro)
- Flunitrazepam (nke 7-nitro analog)
- Flualprazolam (nke sitere na triazolo)
- Ro20-8552
Ntụaka[dezie | dezie ebe o si]
- ↑ US Patent 3371085 5-aryl-3h-1,4-benzodiazepin-2(1h)-ones
- ↑ (August 2002) "Utilization of psychotropic drugs in Taiwan: an overview of outpatient sector in 2000". Zhonghua Yi Xue Za Zhi (Chinese Medical Journal; Free China Ed) 65 (8): 378–91. PMID 12455808.
- ↑ Benzodiazepine Names. non-benzodiazepines.org.uk. Archived from the original on 2008-12-08. Retrieved on 2008-12-29.
- ↑ (February 1994) "A Fourier transform-Raman and infrared vibrational study of delorazepam, fludiazepam, flurazepam, and tetrazepam". Journal of Pharmaceutical Sciences 83 (2): 143–51. DOI:10.1002/jps.2600830207. PMID 7909552.
- ↑ US Patent 3299053 -ARYL-JH-L,X-BENZODIAZEPIN-Z(LH)-ONES
- ↑ (April 1978) "Effects of benzodiazepines and pentobarbitone on the gaba-ergic recurrent inhibition of hippocampal neurons". European Journal of Pharmacology 48 (4): 421–4. DOI:10.1016/0014-2999(78)90169-3. PMID 648585.
- ↑ (January 1985) "Benzodiazepines and their metabolites: relationship between binding affinity to the benzodiazepine receptor and pharmacological activity". Life Sciences 36 (2): 113–9. DOI:10.1016/0024-3205(85)90089-X. PMID 2857046.
- ↑ (1994) "Effect of an anxiolytic on lipid profile in non-insulin-dependent diabetes mellitus". The Journal of International Medical Research 22 (6): 338–42. DOI:10.1177/030006059402200605. PMID 7895897.
- ↑ (1995) "Improvement of stress reduces glycosylated haemoglobin levels in patients with type 2 diabetes". The Journal of International Medical Research 23 (2): 119–22. DOI:10.1177/030006059502300205. PMID 7601294.
- ↑ (1995) "How blood pressure in patients with non-insulin-dependent diabetes mellitus is influenced by stress". The Journal of International Medical Research 23 (5): 377–80. DOI:10.1177/030006059502300508. PMID 8529781.
- ↑ (September 2000) "Screening and determination of benzodiazepines in whole blood using solid-phase extraction and gas chromatography/mass spectrometry". Forensic Science International 113 (1–3): 367–73. DOI:10.1016/S0379-0738(00)00226-7. PMID 10978650.
- ↑ (1993) "[Studies on identification of drugs of abuse by diode array detection. I. Screening-test and identification of benzodiazepines by HPLC-DAD with ICOS software system]". Eisei Shikenjo Hokoku. Bulletin of National Institute of Hygienic Sciences (111): 47–56. PMID 7920567.