Jump to content

Ihe eji eme ihe

Shí Wikipedia, njikotá édémédé nke onyobulạ

Tocolytics (nke a na-akpọkwa ọgwụ mgbochi mgbochi ma ọ bụ ihe na-egbochi ọrụ) bụ ọgwụ eji egbochi ịmụ nwa n'oge (site na Grik τόκος tókos, "amụ nwa", naλύσις lúsis, "ịdị mfe"). Ịmụ nwa n'oge na-akpata 70% nke ọnwụ nwa ọhụrụ.[1] Ya mere, a na-enye ọgwụgwọ tocolytic mgbe ịmụ nwa ga-akpata ịmụ nwa n'oge, na-egbu oge ịmụ nwa ogologo oge maka inye glucocorticoids, nke na-eme ka ọganihu nke akpa ume nwa ma ọ nwere ike ịchọ otu ụbọchị ma ọ bụ abụọ iji rụọ ọrụ.

Ọgwụ tocolytic a na-ejikarị eme ihe gụnyere β2 agonists, calcium channel blockers, NSAIDs, na magnesium sulfate. Ndị a nwere ike inye aka n'ịgbasa oge ịmụ nwa n'oge site n'igbochi mgbanaka nke uru ahụ dị n'akpa nwa ma jiri ha mee ihe iji belata ọrịa na ọnwụ nke nwa e bu n'afọ na-emetụta ịmụ nwa n"oge. Mgbochi nke mgbochi na-abụkarị naanị akụkụ na tocolytics nwere ike ịdabere na ya iji gbuo oge ịmụ nwa ruo ụbọchị ole na ole. Dabere na tocolytic tocolytics eji eme ihe, nwanyị dị ime ma ọ bụ nwa e bu n'afọ nwere ike ịchọ nlekota (dịka, nlekota ọbara mgbali elu mgbe ejiri nifedipine mee ihe ka ọ na-ebelata ọbara mgbali; cardiotocography iji nyochaa ọdịmma nwa e bu). N'ọnọdụ ọ bụla, ihe ize ndụ nke ịmụ nwa n'oge na-adịghị anya naanị na-eme ka ọ dị mma ịbanye n'ụlọ ọgwụ.

Ihe Ndị Na-egosi[dezie | dezie ebe o si]

A na-eji ọgwụ Tocolytics eme ihe n'oge a na-amụ nwa, nke na-ezo aka na mgbe a mụrụ nwa n'oge tupu izu iri atọ na asa nke ime ime. Dị ka ịmụ nwa n'oge na-anọchite anya otu n'ime ihe ndị na-akpata ọrịa na ọnwụ nke nwa ọhụrụ, ebumnuche bụ igbochi ọrịa na ọnwụ nwa ọhụrụ site na igbu oge ịmụ nwa na ịbawanye afọ ime site n'inweta oge maka usoro nchịkwa ndị ọzọ dị ka ọgwụgwọ corticosteroids nke nwere ike inyere aka na ntozu nke akpa ume nwa.[2][3] A na-atụle ọgwụ Tocolytics maka ụmụ nwanyị nwere ọrụ nwa n'oge n'etiti izu ịrị abụọ na anọ na iri atọ na anọ nke afọ ime ma jiri ya na usoro ọgwụgwọ ndị ọzọ nwere ike ịgụnye nlekọta corticosteroids, neuroprotection nke nwa e bu n'afọ, na mbufe dị nchebe na ụlọ ọrụ.[4]

Enweghị ihe doro anya nke mbụ tocolytic.[5][6] Ihe akaebe dị ugbu a na-egosi na ọgwụgwọ mbụ na β2 agonists, calcium channel blocker, ma ọ bụ NSAIDs iji gbatịkwuo ime ruo awa iri anọ na asatọ bụ ụzọ kachasị mma iji nye oge maka nlekọta glucocorticoid.[1]

A na-eji ụdị ihe dị iche iche eme ihe, na-enwe ọnụego ihe ịga nke ọma dịgasị iche iche na mmetụta ndị ọzọ. U.S. ndi nchikota baka nri na ọgwụ (FDA) anaghị akwado ọgwụ ụfọdụ maka iji ya mee iji kwụsị mgbanaka akpa nwa n'oge a na-amụ nwa, kama iji ya mee ka ọ ghara ịbụ aha.

Dabere na nyocha Cochrane nke afọ Puku niri abụọ na iri abụo , tocolytics kachasị dị irè maka igbu oge ịmụ nwa n'oge site na awa iri anọ na asatọ, na ụbọchị nke asa bụ ndị na-enye nitric oxide, ndị na-egbochi ọwa calcium, ndị na'ahụ maka ndị na-anabata oxytocin na njikọta nke tocolyics.[7]

  1. 1.0 1.1 American College of Obstetricians Gynecologists' Committee on Practice Bulletins—Obstetrics (2016). "Practice Bulletin No. 171: Management of Preterm Labor" (in en-US). Obstetrics & Gynecology 128 (4): e155–e164. DOI:10.1097/AOG.0000000000001711. ISSN 0029-7844. PMID 27661654.  Kpọpụta njehie: Invalid <ref> tag; name ":5" defined multiple times with different content
  2. Ouzounian (2010). Management of Common Problems in Obstetrics and Gynecology.. Blackwell Publishing Ltd, 9–11. ISBN 9781444323030. 
  3. Harrison (2016). "Global burden of prematurity". Seminars in Fetal & Neonatal Medicine 21 (2): 74–79. DOI:10.1016/j.siny.2015.12.007. ISSN 1878-0946. PMID 26740166. 
  4. Hanley (2019). "Tocolysis: A Review of the Literature". Obstetrical & Gynecological Survey 74 (1): 50–55. DOI:10.1097/OGX.0000000000000635. ISSN 1533-9866. PMID 30648727. 
  5. (May 2006) "Tocolytic treatment for the management of preterm labour: a systematic review". Singapore Med J 47 (5): 361–6. PMID 16645683. 
  6. (2009) "Adverse drug reactions to tocolytic treatment for preterm labour: prospective cohort study". BMJ 338: b744. DOI:10.1136/bmj.b744. PMID 19264820. 
  7. Wilson (10 August 2022). "Tocolytics for delaying preterm birth: a network meta-analysis (0924)". Cochrane Database of Systematic Reviews 2022 (8): CD014978. DOI:10.1002/14651858.CD014978.pub2. PMID 35947046.