Mensacarcin
Mensacarcin bụ polyketide nke nkuku ume nke mbụ e wepụtara site na nje bakiteria Streptomyces bottropensis bi n'ala.[1][2]
Molekul bụ metabolite nke abụọ, a pụkwara inweta ya n'ụbara site n'ihe na-emepụta ya.[2]
N'ihi ihe maka akparamagwa pụrụ iche ọ bụ ihe nlereanya dị mkpa maka mmepe ọgwụ megide melanoma na ọrịa kansa ndị ọzọ.
Akparamagwa ọgwụ
[dezie | dezie ebe o si]Na NCI-60 mgbochi ọrịa kansa, mensacarcin nlecha nwere mmetụta cytostatic dị elu megide ihe fọrọ nke nta ka ọ bụrụ usoro mkpụrụ ndụ niile (nkezi nke pasenti iri ise mgbochi uto) na mmetụta cytotoxic na-ahọrọ megide mkpụrụ ndụ melanoma.[1]
- ↑ 1.0 1.1
Plitzko (26 October 2017). "The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cells". The Journal of Biological Chemistry 292 (51): 21102–21116. DOI:10.1074/jbc.M116.774836. PMID 29074620.
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<ref>tag; name "Plitzko" defined multiple times with different content - ↑ 2.0 2.1
Lundeberg (4 January 2018). Dirt-dwelling microbe produces potential anti-melanoma weapon. phys.org. Science X. Retrieved on 5 January 2018.Lundeberg, Steve (4 January 2018). "Dirt-dwelling microbe produces potential anti-melanoma weapon". phys.org. Science X. Retrieved 5 January 2018.
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