Mensacarcin
Mensacarcin bụ polyketide nke nkuku ume nke mbụ e wepụtara site na nje bakiteria Streptomyces bottropensis bi n'ala.[1][2] Lundeberg, Steve (4 January 2018). "Dirt-dwelling microbe produces potential anti-melanoma weapon". phys.org. Science X. Retrieved 5 January 2018.Lundeberg, Steve (4 January 2018). "Dirt-dwelling microbe produces potential anti-melanoma weapon". phys.org. Science X. Retrieved 5 January 2018. </ref>
Molekul bụ metabolite nke abụọ, a pụkwara inweta ya n'ụbara site n'ihe na-emepụta ya.[2]
N'ihi ihe maka akparamagwa pụrụ iche ọ bụ ihe nlereanya dị mkpa maka mmepe ọgwụ megide melanoma na ọrịa kansa ndị ọzọ.
Akparamagwa ọgwụ
[dezie | dezie ebe o si]Na NCI-60 mgbochi ọrịa kansa, mensacarcin nlecha nwere mmetụta cytostatic dị elu megide ihe fọrọ nke nta ka ọ bụrụ usoro mkpụrụ ndụ niile (nkezi nke pasenti iri ise mgbochi uto) na mmetụta cytotoxic na-ahọrọ megide mkpụrụ ndụ melanoma.[1]
Plitzko, Birte (26 October 2017). "The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cells". The Journal of Biological Chemistry. 292 (51): 21102–21116. doi:10.1074/jbc.M116.774836. PMID 29074620.{{cite cite journal}}: CS1 maint: unflagged free DOI (link)Plitzko, Birte; Kaweesa, Elizabeth N.; Loesgen, Sandra (26 October 2017). "The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cells". The Journal of Biological Chemistry. 292 (51): 21102–21116. doi:10.1074/jbc.M116.774836. PMC 5743083. PMID 29074620.
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- 1 2
Plitzko, Birte (26 October 2017). "The natural product mensacarcin induces mitochondrial toxicity and apoptosis in melanoma cells". The Journal of Biological Chemistry. 292 (51): 21102–21116. doi:10.1074/jbc.M116.774836. PMID 29074620.
{{cite cite journal}}: CS1 maint: unflagged free DOI (link) - 1 2 Lundeberg, Steve (4 January 2018). "Dirt-dwelling microbe produces potential anti-melanoma weapon". phys.org. Science X. Retrieved 5 January 2018.