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Carbromal

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Templeeti:Chembox

Carbromal bụ ọgwụ hypnotic / sedative nke Bayer mepụtara na 1909 ma mesịa ree ya dị ka Adalin.[1] Parke-Davis mechara ree ọgwụ ahụ na pentobarbital, n'okpuru aha Carbrital.[2]

Nchịkọta

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Carbromal synthesis: Literature:[3][4][5][6]

Diethylmalonic acid [510-20-3] (1) bụ decarboxylated ka ọ bụrụ 2-ethylvaleric acid [20225-24-5] (2). Mgbanwe Hell-Volhard-Zelinsky na-agbanwe ndị na ụdị nke ụwa họrọ site na iji bịa nke a na 2-Bromo-2-Ethylbutyryl Bromide [26074-53-3] (3). Mmetụta ya na urea na affords carbromal (4).

Ntụaka

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  1. (March 1955) "A purpuric drug eruption caused by carbromal". British Medical Journal 1 (4914): 645–6. DOI:10.1136/bmj.1.4914.645. PMID 13230580. 
  2. (1979) Physicians' Desk Reference., 33, Oradell, N.J.: Medical Economics Co, 1266. ISBN 0-87489-999-0. OCLC 4636066. 
  3. Frdl. 10, 1160
  4. Chem. Zentralbl. 1910, II, 1008.
  5. (1931) Grundriss der modernen Arzneistoff‐Synthese. Stuttgart: Verlag Ferd. Enke. 
  6. H. P. Kaufmann, Arzneimittel-Synthese (Berlin, 1953).